By Samantha Mitzel, Gracie F Faculty Mentor: Dr. Deborah O’Dell Abstract Alzheimer’s disease is a debilitating, neurodegenerative disease that is diagnosed with the build-up of neurofibrillary tangles(NFTs) and amyloid plaques. Various studies on Alzheimer’s investigate mechanisms that can prevent NFT build-up, including the micropinocytosis of fibril. Heparin Sulfate Proteoglycans(HSPGs) have been observed to be a…