By Mikyas Telahun, Meah Katz, Kristy Bagley Faculty Mentor: Dr. Deborah O’Dell Abstract Neuroinflammation, driven by proinflammatory cytokines, is linked to Alzheimer’s Disease (AD). Norepinephrine (NE) activates microglial adrenergic receptors, potentially increasing IL-1B production. This study investigates the effects of chromic NE exposure on IL-1β production in human microglial cells, using receptor-specific antagonists (prazosin for…